{
  "_id": "6a103128acfb0bcc41c967a8",
  "Package": "UBCRM",
  "Type": "Package",
  "Title": "Simulate and Conduct Dose-Escalation Phase I Studies",
  "Version": "1.0.3",
  "Date": "2024-04-25",
  "Author": "Benjamin Esterni with contribution from Baboukar Mane",
  "Maintainer": "Christophe Zemmour <christophe.zemmour@gmail.com>",
  "Description": "Two Phase I designs are implemented in the package: the\nclassical 3+3 and the Continual Reassessment Method\n(<doi:10.2307/2531628>). Simulations tools are also available\nto estimate the operating characteristics of the methods with\nseveral user-dependent options.",
  "License": "GPL (>= 2)",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-12 09:08:34 UTC",
    "User": "root"
  },
  "Repository": "https://zemmourc.r-universe.dev",
  "Date/Publication": "2024-04-27 02:33:17 UTC",
  "RemoteUrl": "https://github.com/cran/UBCRM",
  "RemoteRef": "HEAD",
  "RemoteSha": "fa3636355521dc92b82d9e5430f03f671bf9efca",
  "MD5sum": "0596c2ef0088987293d587797970a43d",
  "_user": "zemmourc",
  "_type": "src",
  "_file": "UBCRM_1.0.3.tar.gz",
  "_fileid": "d3993108637b27a7b9efb25eba4ba725dcbea890455befa2dcfea50891f653cf",
  "_filesize": 145027,
  "_sha256": "d3993108637b27a7b9efb25eba4ba725dcbea890455befa2dcfea50891f653cf",
  "_created": "2026-05-12T09:08:34.000Z",
  "_published": "2026-05-22T10:34:16.589Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 77362657483,
      "time": 111,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "6940098376"
    },
    {
      "job": 77362657826,
      "time": 94,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "6940092611"
    },
    {
      "job": 77362657554,
      "time": 168,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "6940189793"
    },
    {
      "job": 77362657409,
      "time": 135,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "6940218756"
    },
    {
      "job": 77362656900,
      "time": 151,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "6940059583"
    },
    {
      "job": 77362656981,
      "time": 78,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7158447179"
    },
    {
      "job": 77362657504,
      "time": 86,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "6940090040"
    },
    {
      "job": 77362657422,
      "time": 56,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "6940079576"
    },
    {
      "job": 77362657660,
      "time": 57,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "6940080122"
    }
  ],
  "_buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/cran/UBCRM",
  "_commit": {
    "id": "fa3636355521dc92b82d9e5430f03f671bf9efca",
    "author": "Christophe Zemmour <christophe.zemmour@gmail.com>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 1.0.3\n",
    "time": 1714185197
  },
  "_maintainer": {
    "name": "Christophe Zemmour",
    "email": "christophe.zemmour@gmail.com",
    "login": "zemmourc",
    "uuid": 181824078
  },
  "_registered": true,
  "_dependencies": [],
  "_owner": "cran",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 0,
  "_contributors": [
    {
      "user": "zemmourc",
      "count": 2,
      "uuid": 181824078
    }
  ],
  "_userbio": {
    "uuid": 181824078,
    "type": "user",
    "name": "zemmourc"
  },
  "_downloads": {
    "count": 592,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/UBCRM"
  },
  "_searchresults": 9,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/UBCRM.html",
    "manual.pdf"
  ],
  "_realowner": "zemmourc",
  "_cranurl": false,
  "_releases": [
    {
      "version": "1.0",
      "date": "2014-01-20"
    },
    {
      "version": "1.0.1",
      "date": "2015-02-20"
    },
    {
      "version": "1.0.2",
      "date": "2022-05-16"
    },
    {
      "version": "1.0.3",
      "date": "2024-04-26"
    }
  ],
  "_exports": [
    "ail1",
    "ail2",
    "aip",
    "ait1",
    "ait2",
    "CreData",
    "Crm",
    "fl",
    "fp",
    "ft",
    "Ll",
    "Lp",
    "Lt",
    "psil",
    "psip",
    "psit",
    "sim3p3",
    "simCrm",
    "ssim3p3",
    "ssimCrm",
    "troisPtrois",
    "updata"
  ],
  "_help": [
    {
      "page": "UBCRM-package",
      "title": "UBCRM is a package containing functions to simulate and conduct dose escalation phase I studies",
      "topics": [
        "UBCRM-package",
        "UBCRM"
      ]
    },
    {
      "page": "aip",
      "title": "Functions to calculate the appropriate dose level singletons",
      "topics": [
        "ail1",
        "ail2",
        "aip",
        "ait1",
        "ait2"
      ]
    },
    {
      "page": "CreData",
      "title": "Creates a CRM dataframe",
      "topics": [
        "CreData"
      ]
    },
    {
      "page": "Crm",
      "title": "Dose-escalation with the Continual Reassessment Method",
      "topics": [
        "Crm"
      ]
    },
    {
      "page": "fp",
      "title": "Density functions",
      "topics": [
        "fl",
        "fp",
        "ft"
      ]
    },
    {
      "page": "Lp",
      "title": "Likelihood functions",
      "topics": [
        "Ll",
        "Lp",
        "Lt"
      ]
    },
    {
      "page": "psip",
      "title": "Dose-Toxicity modelisation functions",
      "topics": [
        "psil",
        "psip",
        "psit"
      ]
    },
    {
      "page": "sim3p3",
      "title": "Simulation of one dose-escalation study with the classical 3+3 design",
      "topics": [
        "sim3p3"
      ]
    },
    {
      "page": "simCrm",
      "title": "Simulation of one dose-escalation study with the Continual Reassessment Method",
      "topics": [
        "simCrm"
      ]
    },
    {
      "page": "ssim3p3",
      "title": "Simulation of n dose-escalation study with the 3+3 design",
      "topics": [
        "ssim3p3"
      ]
    },
    {
      "page": "ssimCrm",
      "title": "Simulation of n dose-escalation study with the Continual Reassessment Method",
      "topics": [
        "ssimCrm"
      ]
    },
    {
      "page": "troisPtrois",
      "title": "Dose escalation with the 3+3 design",
      "topics": [
        "troisPtrois"
      ]
    },
    {
      "page": "updata",
      "title": "Update the CRM dataframe after new patients' collected data",
      "topics": [
        "updata"
      ]
    }
  ],
  "_rundeps": [],
  "_score": 1,
  "_indexed": true,
  "_nocasepkg": "ubcrm",
  "_universes": [
    "zemmourc"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.3",
      "date": "2026-05-12T09:10:29.000Z",
      "distro": "noble",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "22a20206f1d01e719ac9475125001df52f8f2f4037ff6bcb6f1b60a42a3011bc",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.0.3",
      "date": "2026-05-12T09:10:13.000Z",
      "distro": "noble",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "4afba3dab546931060abb767d2034f4f337a198d2abf1de5167278ddf1613c05",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.0.3",
      "date": "2026-05-12T09:14:45.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "2e2384c5633c554102af0f6159a1208140a98d1c96ef48d3e90b2901f1b718a8",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.0.3",
      "date": "2026-05-12T09:16:11.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "3a3d8c6d6fd60432722ade5dda3eb49fb147109361c1aacf9bd3927a7095d96d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-05-12T09:09:47.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "3ad9c2bc3400e008a022859790d44529b755189acbb669214f180148aef5bfa4",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-05-12T09:09:31.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "0d80a9919ddb359ecc29ba8eb5a185de5def36867d3d28ad13741f0d8b2d2d2b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-05-12T09:09:33.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "76100036568903211e727020b50f2539488bc2e7b61df5e45305dbea48d0f5b4",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.0.3",
      "date": "2026-05-22T10:33:57.000Z",
      "commit": "fa3636355521dc92b82d9e5430f03f671bf9efca",
      "fileid": "1a2687fd961670e12988ff49962eb279e89cdc33a650a54573ba8a9e92138fd9",
      "status": "success",
      "buildurl": "https://github.com/r-universe/zemmourc/actions/runs/25724636088"
    }
  ]
}